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GEMMs as preclinical models for testing pancreatic cancer therapies

Pancreatic ductal adenocarcinoma is the most common form of pancreatic tumour, with a very limited survival rate and currently no available disease-modifying treatments. Despite recent advances in the production of genetically engineered mouse models (GEMMs), the development of new therapies for pan...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Gopinathan, Aarthi, Morton, Jennifer P., Jodrell, Duncan I., Sansom, Owen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610236/
https://ncbi.nlm.nih.gov/pubmed/26438692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021055
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