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The lysosomal enzyme receptor protein (LERP) is not essential, but is implicated in lysosomal function in Drosophila melanogaster

The lysosomal enzyme receptor protein (LERP) of Drosophila melanogaster is the ortholog of the mammalian cation-independent mannose 6-phosphate (Man 6-P) receptor, which mediates trafficking of newly synthesized lysosomal acid hydrolases to lysosomes. However, flies lack the enzymes necessary to mak...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Hasanagic, Medina, van Meel, Eline, Luan, Shan, Aurora, Rajeev, Kornfeld, Stuart, Eissenberg, Joel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610224/
https://ncbi.nlm.nih.gov/pubmed/26405051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.013334
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