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The Use of Transcription Terminators to Generate Transgenic Lines of Chinese Hamster Ovary Cells (CHO) with Stable and High Level of Reporter Gene Expression

Mammalian cell lines are widely used to produce recombinant proteins. Stable transgenic cell lines usually contain many insertions of the expression vector in one genomic region. Transcription through transgene can be one of the reasons for target gene repression after prolonged cultivation of cell...

詳細記述

保存先:
書誌詳細
出版年:Acta Naturae
主要な著者: Gasanov, N. B., Toshchakov, S. V., Georgiev, P. G., Maksimenko, O. G.
フォーマット: Artigo
言語:Inglês
出版事項: A.I. Gordeyev 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610167/
https://ncbi.nlm.nih.gov/pubmed/26483962
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