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Competitive inhibition can linearize dose-response and generate a linear rectifier
Many biological responses require a dynamic range that is larger than standard bi-molecular interactions allow, yet the also ability to remain off at low input. Here we mathematically show that an enzyme reaction system involving a combination of competitive inhibition, conservation of the total lev...
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| Publicado no: | Cell Syst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4610030/ https://ncbi.nlm.nih.gov/pubmed/26495436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2015.09.001 |
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