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Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy

Autophagy is an important homeostatic mechanism that eliminates long-lived proteins, protein aggregates and damaged organelles. Its dysregulation is involved in many neurodegenerative disorders. Autophagy is therefore a promising target for blunting neurodegeneration. We searched for novel autophagi...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Moruno Manchon, Jose Felix, Uzor, Ndidi-Ese, Dabaghian, Yuri, Furr-Stimming, Erin E., Finkbeiner, Steven, Tsvetkov, Andrey S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609990/
https://ncbi.nlm.nih.gov/pubmed/26477494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15213
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