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A TRPM4-dependent current in murine renal primary cilia

Defects in primary cilia lead to a variety of human diseases. One of these, polycystic kidney disease, can be caused by defects in a Ca(2+)-gated ion channel (TRPP2) found on the cilium. Other ciliary functions also contribute to cystogenesis, and defects in apical Ca(2+) homeostasis have been impli...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Flannery, Richard J., Kleene, Nancy K., Kleene, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609916/
https://ncbi.nlm.nih.gov/pubmed/26290373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00294.2015
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