Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response

BACKGROUND: This retrospective study aims to investigate the activity of retreatment with anti-EGFR-based therapies in order to explore the concept of clonal evolution by evaluating the impact of prior activity and intervening time interval. METHODS: Eighty-nine KRAS exon 2-wild-type metastatic colo...

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Udgivet i:BMC Cancer
Main Authors: Liu, X., George, G. C., Tsimberidou, A. M., Naing, A., Wheler, J. J., Kopetz, S., Fu, S., Piha-Paul, S. A., Eng, C., Falchook, G. S., Janku, F., Garrett, C., Karp, D., Kurzrock, R., Zinner, R., Raghav, K., Subbiah, V., Hess, K., Meric-Bernstam, F., Hong, D. S., Overman, M. J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609167/
https://ncbi.nlm.nih.gov/pubmed/26474549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1701-3
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