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Wnt signaling in age-related macular degeneration: human macular tissue and mouse model
BACKGROUND: The wingless-type MMTV integration site (Wnt) signaling is a group of signal transduction pathways. In canonical Wnt pathway, Wnt ligands bind to low-density lipoprotein receptor-related protein 5 or 6 (LRP5 or LRP6), resulting in phosphorylation and activation of the receptor. We hypoth...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609061/ https://ncbi.nlm.nih.gov/pubmed/26476672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0683-x |
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