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Wnt signaling in age-related macular degeneration: human macular tissue and mouse model

BACKGROUND: The wingless-type MMTV integration site (Wnt) signaling is a group of signal transduction pathways. In canonical Wnt pathway, Wnt ligands bind to low-density lipoprotein receptor-related protein 5 or 6 (LRP5 or LRP6), resulting in phosphorylation and activation of the receptor. We hypoth...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Tuo, Jingsheng, Wang, Yujuan, Cheng, Rui, Li, Yichao, Chen, Mei, Qiu, Fangfang, Qian, Haohua, Shen, Defen, Penalva, Rosana, Xu, Heping, Ma, Jian-Xing, Chan, Chi-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609061/
https://ncbi.nlm.nih.gov/pubmed/26476672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0683-x
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