Wnt signaling in age-related macular degeneration: human macular tissue and mouse model

BACKGROUND: The wingless-type MMTV integration site (Wnt) signaling is a group of signal transduction pathways. In canonical Wnt pathway, Wnt ligands bind to low-density lipoprotein receptor-related protein 5 or 6 (LRP5 or LRP6), resulting in phosphorylation and activation of the receptor. We hypoth...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Tuo, Jingsheng, Wang, Yujuan, Cheng, Rui, Li, Yichao, Chen, Mei, Qiu, Fangfang, Qian, Haohua, Shen, Defen, Penalva, Rosana, Xu, Heping, Ma, Jian-Xing, Chan, Chi-Chao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609061/
https://ncbi.nlm.nih.gov/pubmed/26476672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0683-x
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