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Lighting up G protein-coupled purinergic receptors with engineered fluorescent ligands

The use of G protein-coupled receptors fluorescent ligands is undergoing continuous expansion. In line with this, fluorescent agonists and antagonists of high affinity for G protein-coupled adenosine and P2Y receptors have been shown to be useful pharmacological probe compounds. Fluorescent ligands...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Ciruela, Francisco, Fernández-Dueñas, Víctor, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608850/
https://ncbi.nlm.nih.gov/pubmed/25890205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.04.001
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