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Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model

Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy. However, these previous studies utilized ado...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Galvan, Daniel L., O’Neil, Richard T., Foster, Aaron E., Huye, Leslie, Bear, Adham, Rooney, Cliona M., Wilson, Matthew H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608718/
https://ncbi.nlm.nih.gov/pubmed/26473608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140744
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