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Bridging between NMA and Elastic Network Models: Preserving All-Atom Accuracy in Coarse-Grained Models

Dynamics can provide deep insights into the functional mechanisms of proteins and protein complexes. For large protein complexes such as GroEL/GroES with more than 8,000 residues, obtaining a fine-grained all-atom description of its normal mode motions can be computationally prohibitive and is often...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Na, Hyuntae, Jernigan, Robert L., Song, Guang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608564/
https://ncbi.nlm.nih.gov/pubmed/26473491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004542
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