High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer

BACKGROUND: Prostate cancer (PC) can be stratified into distinct molecular subtypes based on TMPRSS2-ERG gene fusion status, but its potential prognostic value remains controversial. Likewise, routine clinicopathological features cannot clearly distinguish aggressive from indolent tumors at the time...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Strand, Siri H., Hoyer, Soren, Lynnerup, Anne-Sofie, Haldrup, Christa, Storebjerg, Tine Maj, Borre, Michael, Orntoft, Torben F., Sorensen, Karina D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608326/
https://ncbi.nlm.nih.gov/pubmed/26478752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0146-5
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