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The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family.

Exoenzyme S (ExoS), which has been implicated as a virulence factor of Pseudomonas aeruginosa, catalyzes transfer of the ADP-ribose moiety of NAD+ to many eukaryotic cellular proteins. Its preferred substrates include Ras and several other 21- to 25-kDa GTP-binding proteins. ExoS absolutely requires...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Fu, H, Coburn, J, Collier, R J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8460141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2320
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