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Discovery and optimisation studies of antimalarial phenotypic hits
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were identified. Characterization of these compounds is discussed, along with approaches to optimise the ph...
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| Publicado en: | Eur J Med Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Editions Scientifiques Elsevier
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607724/ https://ncbi.nlm.nih.gov/pubmed/26408453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.08.044 |
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