Circulating Th1 cell-type Tfh cells that exhibit impaired B cell help are preferentially activated during acute malaria in children

Malaria-specific antibody responses are short-lived in children, leaving them susceptible to repeated bouts of febrile malaria. The cellular and molecular mechanisms underlying this apparent immune deficiency are poorly understood. Recently, T follicular helper (Tfh) cells have been shown to play a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Obeng-Adjei, Nyamekye, Portugal, Silvia, Tran, Tuan M., Yazew, Takele B., Skinner, Jeff, Li, Shanping, Jain, Aarti, Felgner, Philip L., Doumbo, Ogobara K., Kayentao, Kassoum, Ongoiba, Aissata, Traore, Boubacar, Crompton, Peter D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607674/
https://ncbi.nlm.nih.gov/pubmed/26440897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.004
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki