Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission

BACKGROUND: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study offered the opportunity to compare amplicon-based 454 ultra-deep sequencing (UDS) a...

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Pubblicato in:PLoS One
Autori principali: Hauser, Andrea, Kuecherer, Claudia, Kunz, Andrea, Dabrowski, Piotr Wojtek, Radonić, Aleksandar, Nitsche, Andreas, Theuring, Stefanie, Bannert, Norbert, Sewangi, Julius, Mbezi, Paulina, Dugange, Festo, Harms, Gundel, Meixenberger, Karolin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607442/
https://ncbi.nlm.nih.gov/pubmed/26469189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140809
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