Zidovudine Exposure in HIV-1 Infected Tanzanian Women Increases Mitochondrial DNA Levels in Placenta and Umbilical Cords

BACKGROUND: Zidovudine (AZT) constitutes part of the recommended regimens for prevention and treatment of HIV-1 infection. At the same time, AZT as well as HIV-1 infection itself may induce mitochondrial damage. In this study, we analyzed the impact of prenatal AZT-exposure on mitochondrial alterati...

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Bibliographic Details
Main Authors: Kunz, Andrea, von Wurmb-Schwark, Nicole, Sewangi, Julius, Ziske, Judith, Lau, Inga, Mbezi, Paulina, Theuring, Stefanie, Hauser, Andrea, Dugange, Festo, Katerna, Angela, Harms, Gundel
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407225/
https://ncbi.nlm.nih.gov/pubmed/22848552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041637
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