Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microglia

BACKGROUND: Inducible nitric oxide synthase (iNOS) makes a great contribution to host defense and inflammation. In many settings, lipopolysaccharide (LPS) induces iNOS expression through activation of the inhibitor of κB-α (IκB-α)-nuclear factor-κB (NF-κB) cascade, whereas interferon-γ (IFN-γ) acts...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Huang, Chao, Lu, Xu, Tong, Lijuan, Wang, Jili, Zhang, Wei, Jiang, Bo, Yang, Rongrong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607096/
https://ncbi.nlm.nih.gov/pubmed/26467650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0406-5
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