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A protein rotaxane controls the translocation of proteins across a ClyA nanopore

Rotaxanes, pseudorotaxanes and catenanes are supramolecular complexes with potential use in nanomachinery, molecular computing and single-molecule studies. Here we constructed a protein rotaxane in which a polypeptide thread is encircled by a Cytolysin A (ClyA) nanopore and capped by two proteins st...

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Bibliographic Details
Published in:Nano Lett
Main Authors: Biesemans, Annemie, Soskine, Misha, Maglia, Giovanni
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606981/
https://ncbi.nlm.nih.gov/pubmed/26243210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.5b02309
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