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Tuning the size and properties of ClyA nanopores assisted by directed evolution

Nanopores have recently emerged as powerful tools in single-molecule investigations. Biological nanopores however have drawbacks, including a fixed size and limited stability in lipid bilayers. Inspired by the great success of directed evolution approaches in tailoring enzymes properties, in this wo...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Soskine, Misha, Biesemans, Annemie, De Maeyer, Marc, Maglia, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410319/
https://ncbi.nlm.nih.gov/pubmed/23919630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4053398
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