The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency

Mutations in the gene encoding the thyroid hormone (TH) transporter, monocarboxylate transporter 8 (MCT8), cause mental retardation in humans associated with a specific thyroid hormone phenotype manifesting high serum T(3) and low T(4) and rT(3) levels. Moreover, these patients have failure to thriv...

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Detalles Bibliográficos
Publicado en:Endocrinology
Autores principales: Ferrara, Alfonso Massimiliano, Liao, Xiao-Hui, Ye, Honggang, Weiss, Roy E., Dumitrescu, Alexandra M., Refetoff, Samuel
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2015
Materias:
Brief Research Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606752/
https://ncbi.nlm.nih.gov/pubmed/26322373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1234
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