Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α

We recently reported that chronic 17β-estradiol (E2) treatment in mice decreases platelet responsiveness, prolongs the tail-bleeding time and protects against acute thromboembolism via the hematopoietic estrogen receptor alpha (ERα), and independently of ERβ. Here, we have explored the respective ro...

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Vydáno v:Endocrinology
Hlavní autoři: Valéra, Marie-Cécile, Fontaine, Coralie, Lenfant, Françoise, Cabou, Cendrine, Guillaume, Maeva, Smirnova, Natalia, Kim, Sung Hoon, Chambon, Pierre, Katzenellenbogen, John A., Katzenellenbogen, Benita S., Payrastre, Bernard, Arnal, Jean-François
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606746/
https://ncbi.nlm.nih.gov/pubmed/26280130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1522
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