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Elevation of ω-3 Polyunsaturated Fatty Acids Attenuates PTEN-deficiency Induced Endometrial Cancer Development through Regulation of COX-2 and PGE(2) Production

Endometrial cancer is one of the most common gynecologic malignancies. Phosphatase and tensin homologue (PTEN)-mutation is frequently identified in endometrial cancer patients. Although high dietary intake of ω-3 polyunsaturated fatty acids (PUFAs) has been associated with reduced risk of endometria...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Pan, Jinshun, Cheng, Lixian, Bi, Xinyun, Zhang, Xin, Liu, Shanshan, Bai, Xiaoming, Li, Fanghong, Zhao, Allan Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606560/
https://ncbi.nlm.nih.gov/pubmed/26468779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14958
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