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Mathematical modelling of local calcium and regulated exocytosis during inhibition and stimulation of glucagon secretion from pancreatic alpha‐cells
KEY POINTS: The control of glucagon secretion from pancreatic alpha‐cells is still unclear and, when defective, is involved in the development of diabetes. We propose a mathematical model of Ca(2+) dynamics and exocytosis to understand better the intracellular mechanisms downstream of electrical act...
Shranjeno v:
| izdano v: | J Physiol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606540/ https://ncbi.nlm.nih.gov/pubmed/26236035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270777 |
| Oznake: |
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