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Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins.

We have designed three zinc-finger proteins with different DNA binding specificities. The design strategy combines a consensus zinc-finger framework sequence with previously characterized recognition regions such that the specificity of each protein is predictable. The first protein consists of thre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Desjarlais, J R, Berg, J M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1993
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC46065/
https://ncbi.nlm.nih.gov/pubmed/8460130
Tagiau: Ychwanegu Tag
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