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Loss of DNA methylation at imprinted loci is a frequent event in hepatocellular carcinoma and identifies patients with shortened survival

BACKGROUND: Aberrant DNA methylation at imprinted loci is an important molecular mechanism contributing to several developmental and pathological disorders including cancer. However, knowledge about imprinting defects due to DNA methylation changes is relatively limited in hepatocellular carcinoma (...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Anwar, Sumadi Lukman, Krech, Till, Hasemeier, Britta, Schipper, Elisa, Schweitzer, Nora, Vogel, Arndt, Kreipe, Hans, Lehmann, Ulrich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606497/
https://ncbi.nlm.nih.gov/pubmed/26473022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0145-6
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