Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis

Interleukin-10 overproduction has been associated with worse prognosis in human cutaneous leishmaniasis, while IFN-γ-dependent responses are associated with parasite killing and host protection. Innovative strategies are needed to overcome therapeutic failure observed in endemic areas. The use of mo...

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Publicado en:J Immunol Res
Autores principales: Castellano, Lucio Roberto, Argiro, Laurent, Dessein, Helia, Dessein, Alain, da Silva, Marcos Vinícius, Correia, Dalmo, Rodrigues, Virmondes
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606169/
https://ncbi.nlm.nih.gov/pubmed/26495321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/152741
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