Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

A solid self-nanoemulsifying drug-delivery system (solid SNEDDS) has been explored to improve the solubility and dissolution profile of glipizide. SNEDDS preconcentrate was systematically optimized using a circumscribed central composite design by varying Captex 355 (Oil), Solutol HS15 (Surfactant)...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Dash, Rajendra Narayan, Mohammed, Habibuddin, Humaira, Touseef, Ramesh, Devi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605912/
https://ncbi.nlm.nih.gov/pubmed/26594119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2015.01.024
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