Why sildenafil and sildenafil citrate monohydrate crystals are not stable?

Sildenafil citrate was crystallized by various techniques aiming to determine the behavior and factors affecting the crystal growth. There are only 2 types of sildenafil obtaining from crystallization: sildenafil (1) and sildenafil citrate monohydrate (2). The used techniques were (i) crystallizatio...

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Veröffentlicht in:Saudi Pharm J
Hauptverfasser: Sawatdee, Somchai, Pakawatchai, Chaveng, Nitichai, Kwanjai, Srichana, Teerapol, Phetmung, Hirihattaya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605910/
https://ncbi.nlm.nih.gov/pubmed/26594116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2015.01.019
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