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Identification of Predictive Cis-Regulatory Elements Using a Discriminative Objective Function and a Dynamic Search Space
The generation of genomic binding or accessibility data from massively parallel sequencing technologies such as ChIP-seq and DNase-seq continues to accelerate. Yet state-of-the-art computational approaches for the identification of DNA binding motifs often yield motifs of weak predictive power. Here...
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Foilsithe in: | PLoS One |
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Main Authors: | , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605740/ https://ncbi.nlm.nih.gov/pubmed/26465884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140557 |
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