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Ab initio identification of functionally interacting pairs of cis-regulatory elements

Cooperatively acting pairs of cis-regulatory elements play important roles in many biological processes. Here, we describe a statistical approach, compositionally orthogonalized co-occurrence analysis (coCOA) that detects pairs of oligonucleotides that preferentially co-occur in pairs of sequence re...

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Detalhes bibliográficos
Main Authors: Friedman, Brad A., Stadler, Michael B., Shomron, Noam, Ding, Ye, Burge, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556269/
https://ncbi.nlm.nih.gov/pubmed/18799692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.080085.108
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