Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential

Fanconi anaemia (FA) is an inherited disorder characterized by chromosomal instability. The phenotype is variable, which raises the possibility that it may be affected by other factors, such as epigenetic modifications. These play an important role in oncogenesis and may be pharmacologically manipul...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Belo, Hélio, Silva, Gabriela, Cardoso, Bruno A., Porto, Beatriz, Minguillon, Jordi, Barbot, José, Coutinho, Jorge, Casado, Jose A., Benedito, Manuela, Saturnino, Hema, Costa, Emília, Bueren, Juan A., Surralles, Jordi, Almeida, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605638/
https://ncbi.nlm.nih.gov/pubmed/26466379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139740
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