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A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells
Genital Chlamydia trachomatis (Ct) infection induces protective immunity that depends on interferon-γ producing CD4 T-cells. By contrast, mucosal exposure to ultraviolet light (UV)-inactivated Ct (UV-Ct) generated regulatory T-cells that exacerbated subsequent Ct infection. We show that mucosal immu...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605428/ https://ncbi.nlm.nih.gov/pubmed/26089520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa8205 |
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