A Homogenous Bioluminescent System for Measuring GTPase, GTPase Activating Protein, and Guanine Nucleotide Exchange Factor Activities

GTPases play a major role in various cellular functions such as cell signaling, cell proliferation, cell differentiation, cytoskeleton modulation, and cell motility. Deregulation or mutation of these proteins has considerable consequences resulting in multiple pathological conditions. Targeting GTPa...

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Vydáno v:Assay Drug Dev Technol
Hlavní autoři: Mondal, Subhanjan, Hsiao, Kevin, Goueli, Said A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605356/
https://ncbi.nlm.nih.gov/pubmed/26167953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.643
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