Robust, tunable genetic memory from protein sequestration combined with positive feedback

Natural regulatory networks contain many interacting components that allow for fine-tuning of switching and memory properties. Building simple bistable switches, synthetic biologists have learned the design principles of complex natural regulatory networks. However, most switches constructed so far...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Shopera, Tatenda, Henson, William R., Ng, Andrew, Lee, Young Je, Ng, Kenneth, Moon, Tae Seok
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Synthetic Biology and Bioengineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605329/
https://ncbi.nlm.nih.gov/pubmed/26384562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv936
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