TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways

In recent times, high-throughput screening analyses have broadly defined the RNA cellular targets of TDP-43, a nuclear factor involved in neurodegeneration. A common outcome of all these studies is that changing the expression levels of this protein can alter the expression of several hundred RNAs w...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: De Conti, Laura, Akinyi, Maureen V., Mendoza-Maldonado, Ramiro, Romano, Maurizio, Baralle, Marco, Buratti, Emanuele
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605304/
https://ncbi.nlm.nih.gov/pubmed/26261209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv814
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