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Development of a new model system to dissect isoform specific Akt signalling in adipocytes
Protein kinase B (Akt) kinases are critical signal transducers mediating insulin action. Genetic studies revealed that Akt1 and Akt2 signalling differentially contribute to sustain lipid and glucose homoeostasis; however Akt isoform-specific effectors remain elusive due to the lack of a suitable mod...
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| Veröffentlicht in: | Biochem J |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604748/ https://ncbi.nlm.nih.gov/pubmed/25856301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150191 |
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