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Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling
The 3 Akt protein kinase isoforms have critical and distinct functions in the regulation of metabolism, cell growth, and apoptosis, yet the mechanisms by which their signaling specificity is achieved remain largely unclear. Here, we investigated potential mechanisms underlying Akt isoform functional...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678468/ https://ncbi.nlm.nih.gov/pubmed/19372382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901933106 |
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