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Bixa orellana leaf extract suppresses histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascade
BACKGROUND: Histamine is established as a potent inflammatory mediator and it is known to increased endothelial permeability by promoting gap formation between endothelial cells. Previous studies have shown that aqueous extract of Bixa orellana leaves (AEBO) exhibits antihistamine activity in vivo,...
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| Veröffentlicht in: | BMC Complement Altern Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604723/ https://ncbi.nlm.nih.gov/pubmed/26468073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-015-0901-3 |
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