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Functional relevance of “seed” and “non-seed” sequences in microRNA-mediated promotion of C. elegans developmental progression
The founding heterochronic microRNAs, lin-4 and let-7, together with their validated targets and well-characterized phenotypes in C. elegans, offer an opportunity to test functionality of microRNAs in a developmental context. In this study, we defined sequence requirements at the microRNA level for...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604436/ https://ncbi.nlm.nih.gov/pubmed/26385508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.053793.115 |
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