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Optimizing the Initial Amikacin Dosage in Adults
We report on the pharmacokinetics (PK) and pharmacodynamics (PD) of high-dose (>15 mg/kg of body weight per day) amikacin. A mean (standard deviation [SD]) maximum drug concentration in the serum (C(max)) and 24-h area under the concentration-time curve (AUC(24)) of 101 (49.4) mg/liter and 600 (3...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604368/ https://ncbi.nlm.nih.gov/pubmed/26282426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01032-15 |
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