The Y3** ncRNA promotes the 3′ end processing of histone mRNAs

We demonstrate that the Y3/Y3** noncoding RNAs (ncRNAs) bind to the CPSF (cleavage and polyadenylation specificity factor) and that Y3** associates with the 3′ untranslated region (UTR) of histone pre-mRNAs. The depletion of Y3** impairs the 3′ end processing of histone pre-mRNAs as well as the form...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Köhn, Marcel, Ihling, Christian, Sinz, Andrea, Krohn, Knut, Hüttelmaier, Stefan
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604341/
https://ncbi.nlm.nih.gov/pubmed/26443846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.266486.115
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