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Symplekin and multiple other polyadenylation factors participate in 3′-end maturation of histone mRNAs

Most metazoan messenger RNAs encoding histones are cleaved, but not polyadenylated at their 3′ ends. Processing in mammalian cell extracts requires the U7 small nuclear ribonucleoprotein (U7 snRNP) and an unidentified heat-labile factor (HLF). We describe the identification of a heat-sensitive prote...

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Autors principals: Kolev, Nikolay G., Steitz, Joan A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276732/
https://ncbi.nlm.nih.gov/pubmed/16230528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1371105
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