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Dynamic enhancer–gene body contacts during transcription elongation

Enhancers govern transcription through multiple mechanisms, including the regulation of elongation by RNA polymerase II (RNAPII). We characterized the dynamics of looped enhancer contacts during synchronous transcription elongation. We found that many distal enhancers form stable contacts with their...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Lee, Kiwon, Hsiung, Chris C.-S., Huang, Peng, Raj, Arjun, Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604340/
https://ncbi.nlm.nih.gov/pubmed/26443845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.255265.114
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