Apoptosis of Oligodendrocytes during Early Development Delays Myelination and Impairs Subsequent Responses to Demyelination

During mammalian development, myelin-forming oligodendrocytes are generated and axons ensheathed according to a tightly regulated sequence of events. Excess premyelinating oligodendrocytes are eliminated by apoptosis and the timing of the onset of myelination in any specific CNS region is highly rep...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Caprariello, Andrew V., Batt, Courtney E., Zippe, Ingrid, Romito-DiGiacomo, Rita R., Karl, Molly, Miller, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604236/
https://ncbi.nlm.nih.gov/pubmed/26468203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1706-15.2015
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