RelA-Induced Interferon Response Negatively Regulates Proliferation

Both oncogenic and tumor-suppressor activities are attributed to the Nuclear Factor kappa B (NF-kB) pathway. Moreover, NF-kB may positively or negatively regulate proliferation. The molecular determinants of these opposing roles of NF-kB are unclear. Using primary human mammary epithelial cells (HME...

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Vydáno v:PLoS One
Hlavní autoři: Kochupurakkal, Bose S., Wang, Zhigang C., Hua, Tony, Culhane, Aedin C., Rodig, Scott J., Rajkovic-Molek, Koraljka, Lazaro, Jean-Bernard, Richardson, Andrea L., Biswas, Debajit K., Iglehart, J. Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604146/
https://ncbi.nlm.nih.gov/pubmed/26460486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140243
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