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Matrix Gla Protein Regulates Calcification of the Aortic Valve

BACKGROUND: The aortic valve interstitial cell (AVIC) has been implicated in the pathogenesis of aortic stenosis. In response to pro-inflammatory stimulation, the AVIC undergoes a phenotypic change from that of a myofibroblast phenotype to that of osteoblast-like cell. Matrix gla-protein (MGP) has b...

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Detalles Bibliográficos
Publicado en:J Surg Res
Autores principales: Venardos, Neil, Bennett, Daine, Weyant, Michael J., Reece, T. Brett, Meng, Xianzhong, Fullerton, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604002/
https://ncbi.nlm.nih.gov/pubmed/25990696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2015.04.076
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