Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

Neuroinflammation is associated with a broad spectrum of neurodegenerative and psychiatric diseases. The core process in neuroinflammation is activation of microglia, the innate immune cells of the brain. We measured the neuroinflammatory response produced by a systemic administration of the Escheri...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sandiego, Christine M., Gallezot, Jean-Dominique, Pittman, Brian, Nabulsi, Nabeel, Lim, Keunpoong, Lin, Shu-Fei, Matuskey, David, Lee, Jae-Yun, O’Connor, Kevin C., Huang, Yiyun, Carson, Richard E., Hannestad, Jonas, Cosgrove, Kelly P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603509/
https://ncbi.nlm.nih.gov/pubmed/26385967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511003112
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