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Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas

The gene encoding the E3 ubiquitin ligase Ligand of Numb protein-X (Lnx)2a is expressed in the ventral-anterior pancreatic bud of zebrafish embryos in addition to its expression in the brain. Knockdown of Lnx2a by using an exon 2/intron 2 splice morpholino resulted in specific inhibition of the diff...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Won, Minho, Ro, Hyunju, Dawid, Igor B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603503/
https://ncbi.nlm.nih.gov/pubmed/26392552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517033112
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